Admission 2019

Faculties

mscbio-science

DR. SALINI BHASKER

SENIOR SCIENTIST

Specialisation: Molecular Biology & Genetic Engineering

Room:

salini.bhasker@scmsgroup.org


Educational Qualifications

  • Doctor of philosophy in Science (PhD): University of Kerala, 2001
  • Master of Philosophy (MPhil): University of Kerala, 1996
  • Master of Science (MSc), University of Kerala, 1993
  • Bachelor of Education (B.Ed), University of Kerala, 1994
  • Bachelor of Science (BSc), University of Kerala, 1991

Employment History

  • Sree Chitra Tirunal Institute for Medical Science and technology (SCTIMST), Trivandrum- 2001 January to 2004 December
  • Assistant Professor – Fatima Mata National College, Kollam, Kerala- 2005 January to 2009 July
  • Senior Scientist- SCMS Institute of Bioscience & Biotechnology Research & Development, South Kalamassery, Cochin, Kerala

Key Responsibilities Held

  • Faculty for M.Sc Molecular Biology & genetic Engineering, B.Sc Botany & Biotechnology, Principal Investigator- DST-WOS Project, Research Guide – Anna University, Chennai, Coordinates the laboratory visits, demonstration of experiments and training programmes for researchers and PG students from external institutes, Universities and colleges., As the part of student customer service programme, provides the technical knowhow and service to the interested candidates, Documentation and filing of ISO, NAAC and DSIR in supporting the Director, Coordination of Internal exams of B.Sc and M.Sc and Coordinates the research activities of the department.

Teaching Interests

  • Biotechnology, Molecular Biology, Biochemistry, Animal cell culture, Genomics

Research Interests

  • Processing of Natural products for the production of drugs, food & biofuel Structural & Functional analysis of genes
  • Expression & Characterization of recombinant therapeutic proteins Invitro models- Diabetes, Wound, Cancer

Publications

International publications

  • Salini Bhasker, Harish Madhav, Mohankumar Chinnamma. Molecular evidence of insulinomimetic property exhibited by steviol and stevioside in diabetes induced L6 and 3T3L1 cells. Phytomedicine 2015, 22, 1037-1044.
  • Mohankumar Chinnamma, Salini Bhasker, Harish Madhav, Rajesh Mamkulathil Devasia, Anisha Shashidharan, Balachandran Chandrasekaran Pillai and Pradeep Thevannoor. Production of Coconut methyl ester (CME) and glycerol from Coconut (Cocos nucifera) oil and the functional feasibility of CME as Biofuel in diesel engine. Fuel, 140 (2015) 4–9.
  • Susan George, Salini Bhasker, Harish Madhav, Archana Nair, C Mohankumar (2014). Functional characterization of recombinant bromelain of Ananas comosus expressed in a prokaryotic system. Molecular Biotechnology 56, 166-174.
  • Krishna K.Yathi, Salini Bhasker, C. Mohankumar (2013) Determination of B cell epitopes and Evaluation of Antigen Capture ELISA for the earlier diagnosis of CHIK Virus using anti-rCHIK E1 rabbit Antibodies. Journal of Immunological methods 393, 45-52
  • Harish Madhav, Salini Bhasker, C Mohankumar (2013) Functional and Structural Variation of Uridine Diphosphate Glycosyltransferase(UGT) gene of Stevia rebaudiana –UGTSr involved in the synthesis of rebaudioside A. Plant Physiology & Biochemistry 63, 245-253
  • Anisha Shashidharan, Salini Bhasker, C Mohankumar (2012). Recombinant Lactoferrin (Lf) of Vechur Cow, the Critical Breed of Bos indicus and the Lf Gene Variants. GENE, 495 (1): 23–28
  • Krishna Kammara Yathi, Julia Mary Joseph, Salini Bhasker, Ramesh Kumar, Mohankumar C (2011). Recombinant CHIK virus E1 coat protein of 11 KDa with antigenic domains for the detection of Chikungunya. Journal of Immunological Methods, 372 (2011) 171–176
  • Anisha Shashidharan, Ruchi Singh, Salini Bhasker, C Mohankumar (2011) Physicochemical Characterization and functional site analysis of lactoferrin gene of Vechur cow, the critical breed of Bos Indicus by bioinformatics approaches. Bioinformation 6(7): 275-278.

National publications

  • Susan George, Salini Bhasker, Rajesh Mamkulathil Devasia, Harish Madhav Warrier1 and Mohankumar Chinnamma. Quantitative PCR (qPCR) data analysis of SOD and its activity and expression in Elettaria cardamomum under biotic stress Biosciences Biotechnology Research Asia, August 2014. Vol. 11(2).
  • A.P. Anugeethu, Salini Bhasker and Chinnamma Mohankumar. Novel Therapeutic Property of Recombinant Human GAPDH Peptide (2013). Biosciences Biotechnology Research Asia, Vol. 10, 751-757
  • Rajesh MD, Salini Bhasker, C Mohankumar (2013) Relative Quantification of FAD2 Gene expression and Comparative Analysis of SNPs of Indian Peanut (Arachis hypogaea L.) Cultivars. Biosciences Biotechnology Research Asia 10(1), 403-410
  • Anju Nandakumar, Salini Bhasker, C Mohankumar (2013) Functional Variation of Ascorbate Peroxidase in Black Pepper (Piper nigrum) Varieties during Infection of Phytophthora capsici. Biosciences Biotechnology Research Asia 10(1), 253-260
  • Sunitha S Sukumaran, Siddharth Banerjee, Salini Bhasker, and Anoopkumar Thekkuveettil: Synaptotagmin 1 translation is regulated through the direct interaction between its own mRNA and the C2A domain. Biochem Biophys Res Commun, 2008, 373: 509-514
  • Sharmila LB, Salini Bhasker, Mathews T Thelly, Boby T Edwin and Mohankumar C; Cloning and sequencing of phytoplasma ribosomal DNA (rDNA) associated with Kerala wilt disease of coconut palms, J. Plant Biochemistry and Biotechnology, 2004, Vol 13, 01-05
  • Salini Bhasker and Mohankumar C; Association of lignifying enzymes in shell synthesis of oil palm fruit (Elaeis guineensis Jacq) dura fruit variety. J. Exp.Biol, 2001, Vol 39, 160-164
  • Salini Bhasker, Minilkumar GL and Mohankumar C; Post harvest changes in mature oil palm fruit pericarp during storage. J. Food Sci. Technol, 1999, Vol 36, 466-468

Book Chapters

  • Siddharth Banerjee, Salini Bhasker, Anoopkumar Thekkuveettil. An inquiry into the molecular mechanism of mesial temporal lobe epilepsy. SILVER LINES, Ed: Kurupath Radhakrishnan, Sree Chitra Tirunal Institute for Medical Science and Technology, Thiruvananthapuram (Publisher), 2004, pp: 190-198.
  • Mohankumar Chinnamma, Anisha Shashidharan and Salini Bhasker. Therapeutic Value of Milk of Vechur Cow, the Indigenous Breed of Kerala Listed as Critical by FAO. Chapter 9: Biodiversity Conservation - Challenges for the Future, 2015, 103-111

Paper Presentations

International

  • Activation of PAI-1 and TGF ?1 gene expression enhances epithelial migration and wound closure using HALE. International Conference on Biotechnology & Biotherapeutics, Sathyabhama University, Chennai, March 8-10th 2017
  • Molecular Mechanism of wound healing property of Hemigraphis colorata using cell line and animal wound model experiments. Proceedings of 3rd GLOBAL AYURVEDA FESTIVAL 31st January to 4th February 2016 at Kozhikode, Kerala. pp.374
  • Production of edible red palm oil and oil cake from oil palm (Elaeis guineensis jacq) fruits by dry method. Emerging technologies for safer foods - INTRADFOOD- EFFoST conference proceedings, SPAIN, pp 1273-1276

National

  • Wound healing effect of Hemigraphis alternata in scratch wound and animal model experiments - A molecular approach, Symposium on “Innovations in biological research for health, disease and environment, at SBC Annual meeting held at CFTRI, Mysore on 21-24th 2016
  • Novel therapeutic property of recombinant human GAPDH peptide. 26th Kerala Science Congress organized by Kerala State Council for Science, Technology and Environment (KSCSTE), January 29-February 1st 2013, Trivandrum. pp- 201
  • Recombinant N-terminal active peptide of bovine (Bos taurus) lactoferrin in suspension cultures of Nicotiana tabacum and its antibacterial sensitivity analysis. 25th Kerala Science Congress organized by Kerala State Council for Science, Technology and Environment (KSCSTE), January 29-31st 2012, Kottayam. PP-209
  • Early Identification of Oil palm varieties. Proceedings of 9th Kerala Science Congress, Trivandrum, Kerala, 1997.

Conferences/seminars/workshops attended

  • International Conference on Biotechnology & Biotherapeutics, Sathyabhama University, Chennai, March 8-10th 2017
  • 3rd GLOBAL AYURVEDA FESTIVAL 31st January to 4th February 2016 at Kozhikode, Kerala.
  • Symposium on “Innovations in biological research for health, disease and environment, at SBC Annual meeting held at CFTRI, Mysore on 21-24th 2016
  • 26th Kerala Science Congress organized by Kerala State Council for Science, Technology and Environment (KSCSTE), January 29-February 1st 2013, Trivandrum. pp- 201
  • 25th Kerala Science Congress organized by Kerala State Council for Science, Technology and Environment (KSCSTE), January 29-31st 2012, Kottayam. PP-209
  • 9th Kerala Science Congress, Trivandrum, Kerala, 1997.

Membership in any professional bodies

  • Society for Applied Biotechnology (FSAB)
  • Society for the Promotion of Oil Palm Research and Development (SOPOPRAD), India
  • Society for Biological Chemist’s India
  • 4Member, Institutional Biosafety Committee (IBSC), SIBBR&D

Special Achievements

  • Women scientist Fellowship – (WOS-A) - SR/WOS-A/LS-252/2009 dated 5/07/2010- (2011- 2014)
  • Women scientist Fellowship (WOS-A) - SR/WOS-A/LS-1030/2014, dated 15-10-2014 (2014-2017)
  • Young Scientist Award- organized by State Committee on Science, Technology and Environment Committee Govt. of Kerala, 1997
  • Young Scientist Award in Technologies organized by 9th Swadeshi Science Congress, Swadeshi Science Movement of Kerala, 1999.

Research Projects Completed

  • Fractionation, Purification and Structural Elucidation of Active Compound of Hemigraphis colorata and studies on its Molecular mechanism of Wound Healing by in vitro and in vivo methods in keratinocytes, 3T3 fibroblasts and in animal models. Department of Science & Technology (DST), Govt. of India, 2014-2017.
  • Regulation of the expression of Insulin receptor (INSR) and glucose transporter (glut4) genes in response to stevioside as an antidiabetic agent in normal and insulin sensitive L6E9 myoblast and T3-L1 preadipocytes- Department of Science & Technology (DST), Govt. of India, 2011-2013.
  • Evaluation of Coconut Embryonic Tissue - Haustorium for the Production of Value Added Products with respect to its Nutritional, Therapeutic and other Biological Properties . Technology Mission, Coconut Development Board, Govt. of India – 2013-2015.

Patents Filed

  • Sequence, Transgenic Products and Process Thereof- Application No. 982/CHE/2011, dated March 29, 2011
  • Nucleotide and Amino acid Sequence, Methods and Kit Thereof Application No. 980/CHE/2011, dated March 28, 2011
  • Coconut Cream obtained from Tender Coconut and Method Thereof- Aapplication no. 5358/che/2013, November 20th 2013
  • Biofuel from Coconut Oil- Application No - 03385/CHE/2013, August 29th 2013

International Patents (Australia)

  • Sequence, Transgenic Products and Process Thereof- Application No. PCT/IB2012/051491, dated March 28th 2012
  • Nucleotide and Amino acid Sequence, Methods and Kit Thereof – Application No. PCT/IB2012/051458, dated March 27th 2012.

Research guideship

  • University of Kerala, Kerala, India
  • Anna University, Chennai, Tamil Nadu, India

Ph.D Supervised

  • Completed -2, Ongoing -1